Hi there 👋

A busy week for the incubator with a number of recordings done and coming to you soon. We have a nice variety of articles today. We reviewed a cochrane review on high vs low cpap, which underscored how little data is out there on the topic. We discussed NAS, which has been rebranded as NOWS, and its effect on cerebral perfusion on brain MRI. We have a bunch of pulmonary articles, looking at NAVA vs SIMV, and this very cool article from germany where researcher constructed a digital model of a BPD baby's lung using MRI and pulmonary function testing. Daphna discussed this great article about parental perspective of their preterm baby's health outcomes, and so much more.

Enjoy this journal club and let us know if you have any feedback or recommendations.

Articles discussed in this week's episode are listed below (in chronological order).

Nasal continuous positive airway pressure levels for the prevention of morbidity and mortality in preterm infants - Bamat, N - 2021 | Cochrane Library
Cerebral perfusion and neurological examination characterise neonatal opioid withdrawal syndrome: a prospective cohort study
Objective To test the hypothesis that cerebral blood flow (CBF) assessed with arterial spin labelling (ASL) MRI is increased and standardised neurological examination is altered in infants with neonatal opioid withdrawal syndrome (NOWS) compared with those without. Design Prospective cohort study.…
Early arterial pressure monitoring and term-equivalent age MRI findings in very preterm infants - Pediatric Research
Pediatric Research - <ArticleTitle Language="En" xml:lang="en">Early arterial pressure monitoring and term-equivalent age MRI findings in very...
Effect of prophylactic dextrose gel on the neonatal gut microbiome
Objective To determine the effect of prophylactic dextrose gel on the infant gut microbiome. Design Observational cohort study nested in a randomised trial. Setting Three maternity hospitals in New Zealand. Patients Infants at risk of neonatal hypoglycaemia whose parents consented to participatio…
Neurally adjusted ventilatory assist in ventilated very preterm infants: A crossover study
ObjectiveTo assess the effects of neurally adjusted ventilatory assist (NAVA) ventilation on oxygenation and respiratory parameters in preterm infants. Study DesignAn observational crossover stu...
In silico numerical simulation of ventilator settings during high‐frequency ventilation in preterm infants
ObjectiveDespite the routine use of antenatal steroids, exogenous surfactants, and different noninvasive ventilation methods, many extremely low gestational age neonates, preterm, and term infants ...
Parental perspective on important health outcomes of extremely preterm infants
Background and objective Neonatal outcome research and clinical follow-up principally focus on neurodevelopmental impairment (NDI) after extremely preterm birth, as defined by the scientific community, without parental input. This survey aimed to investigate parental perspectives about the health an…
Association of Early Amino Acid Intake With Full-Scale IQ Among Very Preterm Infants
This cohort study assesses the association between high amino acid intake among very preterm infants at 7 days after birth and cognitive performance at age 5 years.

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